Aubrey de Grey, a pioneer in life extension research, has suggested 7 strategies under the awkward name Strategies for Engineered Negligible Senescence. These strategies are based on the current understanding of aging and point toward a research agenda for life extension:
- Repair cell loss through exercise, stimulating cell division and the use of stem cells.
- Remove declining (senescent) cells through gene therapy or turning the immune system against them.
- Prevent protein cross-linking through medications.
- Remove toxins and other cellular build up through training the immune system to remove the "garbage."
- Find new enzymes that can break down toxins in the body.
- Use gene therapy to protect mitochondria from free radical damage.
- Use gene therapy to fight cancer by using gene therapy to turn off telomerase that allows cancers cells to replicate without dying.
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